A-15 PTSD Symptoms Are Related to Cognition Following Complicated Mild and Moderate TBI, but Not Severe and Penetrating TBI

Abstract Objective Despite the strong evidence suggesting post-traumatic stress disorder (PTSD) symptoms negatively impact cognition following mild traumatic brain injury (TBI), little is known about this relationship in more severe TBI. This study investigates between PTSD and cognitive performance complicated mild, moderate, severe, penetrating Methods Participants were 137 U.S. military service members veterans (SMVs) with a history of or TBI prospectively enrolled Defense Veterans Brain Injury Center (DVBIC)/Traumatic Excellence (TBICoE) 15-Year Longitudinal Study. divided into two groups: mild/moderate (n = 64) severe/penetrating 73). completed neuropsychological assessment, including Checklist-Civilian Version one year post-injury. Six composite scores an overall test battery mean (OTBM) considered. who failed symptom validity tests excluded. Hierarchical linear regressions conducted evaluating performance. Results severity (βs:-0.163 to −0.253, ps < 0.04) (βs:-0.189 −0.212), 0.03) related sample. Within group, unrelated significantly processing speed (R2Δ 0.080, β −0.284, p 0.016), immediate memory 0.204, −0.453, 0.001), delayed 0.180, −0.426, executive functioning 0.102, −0.319, 0.007), OTBM 0.170, −0.413, 0.001). Discussion was SMVs should be considered when patients moderate